WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for the enriched GO category are listed in this table. For each GO category, the first row lists its sub-root (biological process, molecular function, or cellular component), category name, and corresponding GO ID.
The second row lists the following statistics:
Finally, genes in the category are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:biological process       Name:nervous system development       ID:GO:0007399
C=1724; O=21; E=6.36; R=3.30; rawP=3.04e-07; adjP=5.61e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000092758 NA COL9A3 collagen, type IX, alpha 3 1299 ENSG00000092758
2  ENSG00000125851 NA PCSK2 proprotein convertase subtilisin/kexin type 2 5126 ENSG00000125851
3  ENSG00000185985 NA SLITRK2 SLIT and NTRK-like family, member 2 84631 ENSG00000185985
4  ENSG00000108381 NA ASPA aspartoacylase 443 ENSG00000108381
5  ENSG00000046653 NA GPM6B glycoprotein M6B 2824 ENSG00000046653
6  ENSG00000146013 NA GFRA3 GDNF family receptor alpha 3 2676 ENSG00000146013
7  ENSG00000100146 NA SOX10 SRY (sex determining region Y)-box 10 6663 ENSG00000100146
8  ENSG00000185652 NA NTF3 neurotrophin 3 4908 ENSG00000185652
9  ENSG00000179915 NA NRXN1 neurexin 1 9378 ENSG00000179915
10  ENSG00000181449 NA SOX2 SRY (sex determining region Y)-box 2 6657 ENSG00000181449
11  ENSG00000021645 NA NRXN3 neurexin 3 9369 ENSG00000021645
12  ENSG00000188487 NA INSC inscuteable homolog (Drosophila) 387755 ENSG00000188487
13  ENSG00000184564 NA SLITRK6 SLIT and NTRK-like family, member 6 84189 ENSG00000184564
14  ENSG00000135111 NA TBX3 T-box 3 6926 ENSG00000135111
15  ENSG00000137203 NA TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 7020 ENSG00000137203
16  ENSG00000128872 NA TMOD2 tropomodulin 2 (neuronal) 29767 ENSG00000128872
17  ENSG00000123560 NA PLP1 proteolipid protein 1 5354 ENSG00000123560
18  ENSG00000196338 NA NLGN3 neuroligin 3 54413 ENSG00000196338
19  ENSG00000065361 NA ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 2065 ENSG00000065361
20  ENSG00000149571 NA KIRREL3 kin of IRRE like 3 (Drosophila) 84623 ENSG00000149571
21  ENSG00000198910 NA L1CAM L1 cell adhesion molecule 3897 ENSG00000198910


Database:biological process       Name:transmission of nerve impulse       ID:GO:0019226
C=735; O=14; E=2.71; R=5.16; rawP=2.87e-07; adjP=5.61e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000021645 NA NRXN3 neurexin 3 9369 ENSG00000021645
2  ENSG00000114812 NA VIPR1 vasoactive intestinal peptide receptor 1 7433 ENSG00000114812
3  ENSG00000135643 NA KCNMB4 potassium large conductance calcium-activated channel, subfamily M, beta member 4 27345 ENSG00000135643
4  ENSG00000108381 NA ASPA aspartoacylase 443 ENSG00000108381
5  ENSG00000158887 NA MPZ myelin protein zero 4359 ENSG00000158887
6  ENSG00000046653 NA GPM6B glycoprotein M6B 2824 ENSG00000046653
7  ENSG00000114200 NA BCHE butyrylcholinesterase 590 ENSG00000114200
8  ENSG00000163873 NA GRIK3 glutamate receptor, ionotropic, kainate 3 2899 ENSG00000163873
9  ENSG00000237515 NA SHISA9 shisa homolog 9 (Xenopus laevis) 729993 ENSG00000237515
10  ENSG00000128872 NA TMOD2 tropomodulin 2 (neuronal) 29767 ENSG00000128872
11  ENSG00000123560 NA PLP1 proteolipid protein 1 5354 ENSG00000123560
12  ENSG00000196338 NA NLGN3 neuroligin 3 54413 ENSG00000196338
13  ENSG00000185652 NA NTF3 neurotrophin 3 4908 ENSG00000185652
14  ENSG00000179915 NA NRXN1 neurexin 1 9378 ENSG00000179915


Database:biological process       Name:regulation of synaptic transmission       ID:GO:0050804
C=186; O=8; E=0.69; R=11.65; rawP=3.71e-07; adjP=5.61e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000135643 NA KCNMB4 potassium large conductance calcium-activated channel, subfamily M, beta member 4 27345 ENSG00000135643
2  ENSG00000046653 NA GPM6B glycoprotein M6B 2824 ENSG00000046653
3  ENSG00000114200 NA BCHE butyrylcholinesterase 590 ENSG00000114200
4  ENSG00000163873 NA GRIK3 glutamate receptor, ionotropic, kainate 3 2899 ENSG00000163873
5  ENSG00000237515 NA SHISA9 shisa homolog 9 (Xenopus laevis) 729993 ENSG00000237515
6  ENSG00000196338 NA NLGN3 neuroligin 3 54413 ENSG00000196338
7  ENSG00000185652 NA NTF3 neurotrophin 3 4908 ENSG00000185652
8  ENSG00000179915 NA NRXN1 neurexin 1 9378 ENSG00000179915


Database:biological process       Name:multicellular organismal signaling       ID:GO:0035637
C=751; O=14; E=2.77; R=5.05; rawP=3.73e-07; adjP=5.61e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000021645 NA NRXN3 neurexin 3 9369 ENSG00000021645
2  ENSG00000114812 NA VIPR1 vasoactive intestinal peptide receptor 1 7433 ENSG00000114812
3  ENSG00000135643 NA KCNMB4 potassium large conductance calcium-activated channel, subfamily M, beta member 4 27345 ENSG00000135643
4  ENSG00000108381 NA ASPA aspartoacylase 443 ENSG00000108381
5  ENSG00000158887 NA MPZ myelin protein zero 4359 ENSG00000158887
6  ENSG00000046653 NA GPM6B glycoprotein M6B 2824 ENSG00000046653
7  ENSG00000114200 NA BCHE butyrylcholinesterase 590 ENSG00000114200
8  ENSG00000163873 NA GRIK3 glutamate receptor, ionotropic, kainate 3 2899 ENSG00000163873
9  ENSG00000237515 NA SHISA9 shisa homolog 9 (Xenopus laevis) 729993 ENSG00000237515
10  ENSG00000128872 NA TMOD2 tropomodulin 2 (neuronal) 29767 ENSG00000128872
11  ENSG00000123560 NA PLP1 proteolipid protein 1 5354 ENSG00000123560
12  ENSG00000196338 NA NLGN3 neuroligin 3 54413 ENSG00000196338
13  ENSG00000185652 NA NTF3 neurotrophin 3 4908 ENSG00000185652
14  ENSG00000179915 NA NRXN1 neurexin 1 9378 ENSG00000179915


Database:biological process       Name:synaptic transmission       ID:GO:0007268
C=651; O=13; E=2.40; R=5.41; rawP=4.88e-07; adjP=5.88e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000021645 NA NRXN3 neurexin 3 9369 ENSG00000021645
2  ENSG00000114812 NA VIPR1 vasoactive intestinal peptide receptor 1 7433 ENSG00000114812
3  ENSG00000135643 NA KCNMB4 potassium large conductance calcium-activated channel, subfamily M, beta member 4 27345 ENSG00000135643
4  ENSG00000158887 NA MPZ myelin protein zero 4359 ENSG00000158887
5  ENSG00000046653 NA GPM6B glycoprotein M6B 2824 ENSG00000046653
6  ENSG00000114200 NA BCHE butyrylcholinesterase 590 ENSG00000114200
7  ENSG00000163873 NA GRIK3 glutamate receptor, ionotropic, kainate 3 2899 ENSG00000163873
8  ENSG00000237515 NA SHISA9 shisa homolog 9 (Xenopus laevis) 729993 ENSG00000237515
9  ENSG00000128872 NA TMOD2 tropomodulin 2 (neuronal) 29767 ENSG00000128872
10  ENSG00000123560 NA PLP1 proteolipid protein 1 5354 ENSG00000123560
11  ENSG00000196338 NA NLGN3 neuroligin 3 54413 ENSG00000196338
12  ENSG00000185652 NA NTF3 neurotrophin 3 4908 ENSG00000185652
13  ENSG00000179915 NA NRXN1 neurexin 1 9378 ENSG00000179915


Database:biological process       Name:regulation of transmission of nerve impulse       ID:GO:0051969
C=204; O=8; E=0.75; R=10.62; rawP=7.48e-07; adjP=7.50e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000135643 NA KCNMB4 potassium large conductance calcium-activated channel, subfamily M, beta member 4 27345 ENSG00000135643
2  ENSG00000046653 NA GPM6B glycoprotein M6B 2824 ENSG00000046653
3  ENSG00000114200 NA BCHE butyrylcholinesterase 590 ENSG00000114200
4  ENSG00000163873 NA GRIK3 glutamate receptor, ionotropic, kainate 3 2899 ENSG00000163873
5  ENSG00000237515 NA SHISA9 shisa homolog 9 (Xenopus laevis) 729993 ENSG00000237515
6  ENSG00000196338 NA NLGN3 neuroligin 3 54413 ENSG00000196338
7  ENSG00000185652 NA NTF3 neurotrophin 3 4908 ENSG00000185652
8  ENSG00000179915 NA NRXN1 neurexin 1 9378 ENSG00000179915


Database:biological process       Name:cell-cell signaling       ID:GO:0007267
C=1099; O=16; E=4.06; R=3.94; rawP=1.27e-06; adjP=9.56e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000114812 NA VIPR1 vasoactive intestinal peptide receptor 1 7433 ENSG00000114812
2  ENSG00000046653 NA GPM6B glycoprotein M6B 2824 ENSG00000046653
3  ENSG00000185652 NA NTF3 neurotrophin 3 4908 ENSG00000185652
4  ENSG00000179915 NA NRXN1 neurexin 1 9378 ENSG00000179915
5  ENSG00000181449 NA SOX2 SRY (sex determining region Y)-box 2 6657 ENSG00000181449
6  ENSG00000021645 NA NRXN3 neurexin 3 9369 ENSG00000021645
7  ENSG00000135643 NA KCNMB4 potassium large conductance calcium-activated channel, subfamily M, beta member 4 27345 ENSG00000135643
8  ENSG00000114200 NA BCHE butyrylcholinesterase 590 ENSG00000114200
9  ENSG00000158887 NA MPZ myelin protein zero 4359 ENSG00000158887
10  ENSG00000135111 NA TBX3 T-box 3 6926 ENSG00000135111
11  ENSG00000163873 NA GRIK3 glutamate receptor, ionotropic, kainate 3 2899 ENSG00000163873
12  ENSG00000137203 NA TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 7020 ENSG00000137203
13  ENSG00000237515 NA SHISA9 shisa homolog 9 (Xenopus laevis) 729993 ENSG00000237515
14  ENSG00000123560 NA PLP1 proteolipid protein 1 5354 ENSG00000123560
15  ENSG00000128872 NA TMOD2 tropomodulin 2 (neuronal) 29767 ENSG00000128872
16  ENSG00000196338 NA NLGN3 neuroligin 3 54413 ENSG00000196338


Database:biological process       Name:regulation of neurological system process       ID:GO:0031644
C=217; O=8; E=0.80; R=9.99; rawP=1.19e-06; adjP=9.56e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000135643 NA KCNMB4 potassium large conductance calcium-activated channel, subfamily M, beta member 4 27345 ENSG00000135643
2  ENSG00000046653 NA GPM6B glycoprotein M6B 2824 ENSG00000046653
3  ENSG00000114200 NA BCHE butyrylcholinesterase 590 ENSG00000114200
4  ENSG00000163873 NA GRIK3 glutamate receptor, ionotropic, kainate 3 2899 ENSG00000163873
5  ENSG00000237515 NA SHISA9 shisa homolog 9 (Xenopus laevis) 729993 ENSG00000237515
6  ENSG00000196338 NA NLGN3 neuroligin 3 54413 ENSG00000196338
7  ENSG00000185652 NA NTF3 neurotrophin 3 4908 ENSG00000185652
8  ENSG00000179915 NA NRXN1 neurexin 1 9378 ENSG00000179915


Database:biological process       Name:neurogenesis       ID:GO:0022008
C=1140; O=16; E=4.21; R=3.80; rawP=2.06e-06; adjP=0.0001
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000021645 NA NRXN3 neurexin 3 9369 ENSG00000021645
2  ENSG00000092758 NA COL9A3 collagen, type IX, alpha 3 1299 ENSG00000092758
3  ENSG00000185985 NA SLITRK2 SLIT and NTRK-like family, member 2 84631 ENSG00000185985
4  ENSG00000108381 NA ASPA aspartoacylase 443 ENSG00000108381
5  ENSG00000184564 NA SLITRK6 SLIT and NTRK-like family, member 6 84189 ENSG00000184564
6  ENSG00000137203 NA TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 7020 ENSG00000137203
7  ENSG00000146013 NA GFRA3 GDNF family receptor alpha 3 2676 ENSG00000146013
8  ENSG00000100146 NA SOX10 SRY (sex determining region Y)-box 10 6663 ENSG00000100146
9  ENSG00000123560 NA PLP1 proteolipid protein 1 5354 ENSG00000123560
10  ENSG00000065361 NA ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 2065 ENSG00000065361
11  ENSG00000196338 NA NLGN3 neuroligin 3 54413 ENSG00000196338
12  ENSG00000185652 NA NTF3 neurotrophin 3 4908 ENSG00000185652
13  ENSG00000179915 NA NRXN1 neurexin 1 9378 ENSG00000179915
14  ENSG00000149571 NA KIRREL3 kin of IRRE like 3 (Drosophila) 84623 ENSG00000149571
15  ENSG00000198910 NA L1CAM L1 cell adhesion molecule 3897 ENSG00000198910
16  ENSG00000181449 NA SOX2 SRY (sex determining region Y)-box 2 6657 ENSG00000181449


Database:biological process       Name:neurological system process       ID:GO:0050877
C=1237; O=16; E=4.57; R=3.50; rawP=5.95e-06; adjP=0.0003
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000114812 NA VIPR1 vasoactive intestinal peptide receptor 1 7433 ENSG00000114812
2  ENSG00000108381 NA ASPA aspartoacylase 443 ENSG00000108381
3  ENSG00000046653 NA GPM6B glycoprotein M6B 2824 ENSG00000046653
4  ENSG00000185652 NA NTF3 neurotrophin 3 4908 ENSG00000185652
5  ENSG00000179915 NA NRXN1 neurexin 1 9378 ENSG00000179915
6  ENSG00000181449 NA SOX2 SRY (sex determining region Y)-box 2 6657 ENSG00000181449
7  ENSG00000021645 NA NRXN3 neurexin 3 9369 ENSG00000021645
8  ENSG00000135643 NA KCNMB4 potassium large conductance calcium-activated channel, subfamily M, beta member 4 27345 ENSG00000135643
9  ENSG00000114200 NA BCHE butyrylcholinesterase 590 ENSG00000114200
10  ENSG00000158887 NA MPZ myelin protein zero 4359 ENSG00000158887
11  ENSG00000163873 NA GRIK3 glutamate receptor, ionotropic, kainate 3 2899 ENSG00000163873
12  ENSG00000137203 NA TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 7020 ENSG00000137203
13  ENSG00000237515 NA SHISA9 shisa homolog 9 (Xenopus laevis) 729993 ENSG00000237515
14  ENSG00000123560 NA PLP1 proteolipid protein 1 5354 ENSG00000123560
15  ENSG00000128872 NA TMOD2 tropomodulin 2 (neuronal) 29767 ENSG00000128872
16  ENSG00000196338 NA NLGN3 neuroligin 3 54413 ENSG00000196338


Database:molecular function       Name:RNA polymerase II core promoter proximal region sequence-specific DNA binding       ID:GO:0000978
C=24; O=2; E=0.08; R=25.47; rawP=0.0028; adjP=0.0795
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000100146 NA SOX10 SRY (sex determining region Y)-box 10 6663 ENSG00000100146
2  ENSG00000137203 NA TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 7020 ENSG00000137203


Database:molecular function       Name:RNA polymerase II distal enhancer sequence-specific DNA binding       ID:GO:0000980
C=16; O=2; E=0.05; R=38.21; rawP=0.0012; adjP=0.0795
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000100146 NA SOX10 SRY (sex determining region Y)-box 10 6663 ENSG00000100146
2  ENSG00000137203 NA TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 7020 ENSG00000137203


Database:molecular function       Name:enhancer sequence-specific DNA binding       ID:GO:0001158
C=25; O=2; E=0.08; R=24.45; rawP=0.0030; adjP=0.0795
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000100146 NA SOX10 SRY (sex determining region Y)-box 10 6663 ENSG00000100146
2  ENSG00000137203 NA TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 7020 ENSG00000137203


Database:molecular function       Name:sialyltransferase activity       ID:GO:0008373
C=20; O=2; E=0.07; R=30.57; rawP=0.0019; adjP=0.0795
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000111728 NA ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 6489 ENSG00000111728
2  ENSG00000117069 NA ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 81849 ENSG00000117069


Database:molecular function       Name:enhancer binding       ID:GO:0035326
C=28; O=2; E=0.09; R=21.83; rawP=0.0038; adjP=0.0806
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000100146 NA SOX10 SRY (sex determining region Y)-box 10 6663 ENSG00000100146
2  ENSG00000137203 NA TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 7020 ENSG00000137203


Database:molecular function       Name:core promoter proximal region sequence-specific DNA binding       ID:GO:0000987
C=35; O=2; E=0.11; R=17.47; rawP=0.0058; adjP=0.0939
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000100146 NA SOX10 SRY (sex determining region Y)-box 10 6663 ENSG00000100146
2  ENSG00000137203 NA TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 7020 ENSG00000137203


Database:molecular function       Name:core promoter proximal region DNA binding       ID:GO:0001159
C=36; O=2; E=0.12; R=16.98; rawP=0.0062; adjP=0.0939
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000100146 NA SOX10 SRY (sex determining region Y)-box 10 6663 ENSG00000100146
2  ENSG00000137203 NA TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 7020 ENSG00000137203


Database:molecular function       Name:carboxylesterase activity       ID:GO:0004091
C=39; O=2; E=0.13; R=15.68; rawP=0.0072; adjP=0.0954
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000196338 NA NLGN3 neuroligin 3 54413 ENSG00000196338
2  ENSG00000114200 NA BCHE butyrylcholinesterase 590 ENSG00000114200


Database:molecular function       Name:peptide binding       ID:GO:0042277
C=163; O=3; E=0.53; R=5.63; rawP=0.0162; adjP=0.1656
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000089234 NA BRAP BRCA1 associated protein 8315 ENSG00000089234
2  ENSG00000114200 NA BCHE butyrylcholinesterase 590 ENSG00000114200
3  ENSG00000113494 NA PRLR prolactin receptor 5618 ENSG00000113494


Database:molecular function       Name:alcohol binding       ID:GO:0043178
C=64; O=2; E=0.21; R=9.55; rawP=0.0186; adjP=0.1656
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000147588 NA PMP2 peripheral myelin protein 2 5375 ENSG00000147588
2  ENSG00000114200 NA BCHE butyrylcholinesterase 590 ENSG00000114200


Database:cellular component       Name:integral to plasma membrane       ID:GO:0005887
C=1220; O=13; E=4.29; R=3.03; rawP=0.0003; adjP=0.0150
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000021645 NA NRXN3 neurexin 3 9369 ENSG00000021645
2  ENSG00000114812 NA VIPR1 vasoactive intestinal peptide receptor 1 7433 ENSG00000114812
3  ENSG00000112077 NA RHAG Rh-associated glycoprotein 6005 ENSG00000112077
4  ENSG00000135643 NA KCNMB4 potassium large conductance calcium-activated channel, subfamily M, beta member 4 27345 ENSG00000135643
5  ENSG00000137070 NA IL11RA interleukin 11 receptor, alpha 3590 ENSG00000137070
6  ENSG00000158887 NA MPZ myelin protein zero 4359 ENSG00000158887
7  ENSG00000164626 NA KCNK5 potassium channel, subfamily K, member 5 8645 ENSG00000164626
8  ENSG00000089356 NA FXYD3 FXYD domain containing ion transport regulator 3 5349 ENSG00000089356
9  ENSG00000163873 NA GRIK3 glutamate receptor, ionotropic, kainate 3 2899 ENSG00000163873
10  ENSG00000237515 NA SHISA9 shisa homolog 9 (Xenopus laevis) 729993 ENSG00000237515
11  ENSG00000196338 NA NLGN3 neuroligin 3 54413 ENSG00000196338
12  ENSG00000065361 NA ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 2065 ENSG00000065361
13  ENSG00000179915 NA NRXN1 neurexin 1 9378 ENSG00000179915


Database:cellular component       Name:intrinsic to plasma membrane       ID:GO:0031226
C=1264; O=13; E=4.45; R=2.92; rawP=0.0004; adjP=0.0150
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000021645 NA NRXN3 neurexin 3 9369 ENSG00000021645
2  ENSG00000114812 NA VIPR1 vasoactive intestinal peptide receptor 1 7433 ENSG00000114812
3  ENSG00000112077 NA RHAG Rh-associated glycoprotein 6005 ENSG00000112077
4  ENSG00000135643 NA KCNMB4 potassium large conductance calcium-activated channel, subfamily M, beta member 4 27345 ENSG00000135643
5  ENSG00000137070 NA IL11RA interleukin 11 receptor, alpha 3590 ENSG00000137070
6  ENSG00000158887 NA MPZ myelin protein zero 4359 ENSG00000158887
7  ENSG00000164626 NA KCNK5 potassium channel, subfamily K, member 5 8645 ENSG00000164626
8  ENSG00000089356 NA FXYD3 FXYD domain containing ion transport regulator 3 5349 ENSG00000089356
9  ENSG00000163873 NA GRIK3 glutamate receptor, ionotropic, kainate 3 2899 ENSG00000163873
10  ENSG00000237515 NA SHISA9 shisa homolog 9 (Xenopus laevis) 729993 ENSG00000237515
11  ENSG00000196338 NA NLGN3 neuroligin 3 54413 ENSG00000196338
12  ENSG00000065361 NA ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 2065 ENSG00000065361
13  ENSG00000179915 NA NRXN1 neurexin 1 9378 ENSG00000179915


Database:cellular component       Name:axon       ID:GO:0030424
C=286; O=6; E=1.01; R=5.96; rawP=0.0005; adjP=0.0150
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000179915 NA NRXN1 neurexin 1 9378 ENSG00000179915
2  ENSG00000162951 NA LRRTM1 leucine rich repeat transmembrane neuronal 1 347730 ENSG00000162951
3  ENSG00000154654 NA NCAM2 neural cell adhesion molecule 2 4685 ENSG00000154654
4  ENSG00000149571 NA KIRREL3 kin of IRRE like 3 (Drosophila) 84623 ENSG00000149571
5  ENSG00000198910 NA L1CAM L1 cell adhesion molecule 3897 ENSG00000198910
6  ENSG00000163873 NA GRIK3 glutamate receptor, ionotropic, kainate 3 2899 ENSG00000163873


Database:cellular component       Name:neuron projection       ID:GO:0043005
C=651; O=8; E=2.29; R=3.49; rawP=0.0019; adjP=0.0244
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000237515 NA SHISA9 shisa homolog 9 (Xenopus laevis) 729993 ENSG00000237515
2  ENSG00000128872 NA TMOD2 tropomodulin 2 (neuronal) 29767 ENSG00000128872
3  ENSG00000179915 NA NRXN1 neurexin 1 9378 ENSG00000179915
4  ENSG00000162951 NA LRRTM1 leucine rich repeat transmembrane neuronal 1 347730 ENSG00000162951
5  ENSG00000154654 NA NCAM2 neural cell adhesion molecule 2 4685 ENSG00000154654
6  ENSG00000149571 NA KIRREL3 kin of IRRE like 3 (Drosophila) 84623 ENSG00000149571
7  ENSG00000198910 NA L1CAM L1 cell adhesion molecule 3897 ENSG00000198910
8  ENSG00000163873 NA GRIK3 glutamate receptor, ionotropic, kainate 3 2899 ENSG00000163873


Database:cellular component       Name:intrinsic to membrane       ID:GO:0031224
C=5437; O=31; E=19.13; R=1.62; rawP=0.0011; adjP=0.0244
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000114812 NA VIPR1 vasoactive intestinal peptide receptor 1 7433 ENSG00000114812
2  ENSG00000112077 NA RHAG Rh-associated glycoprotein 6005 ENSG00000112077
3  ENSG00000137070 NA IL11RA interleukin 11 receptor, alpha 3590 ENSG00000137070
4  ENSG00000185985 NA SLITRK2 SLIT and NTRK-like family, member 2 84631 ENSG00000185985
5  ENSG00000046653 NA GPM6B glycoprotein M6B 2824 ENSG00000046653
6  ENSG00000089356 NA FXYD3 FXYD domain containing ion transport regulator 3 5349 ENSG00000089356
7  ENSG00000189409 NA MMP23B matrix metallopeptidase 23B 8510 ENSG00000189409
8  ENSG00000146013 NA GFRA3 GDNF family receptor alpha 3 2676 ENSG00000146013
9  ENSG00000179915 NA NRXN1 neurexin 1 9378 ENSG00000179915
10  ENSG00000117069 NA ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 81849 ENSG00000117069
11  ENSG00000147255 NA IGSF1 immunoglobulin superfamily, member 1 3547 ENSG00000147255
12  ENSG00000021645 NA NRXN3 neurexin 3 9369 ENSG00000021645
13  ENSG00000110900 NA TSPAN11 tetraspanin 11 441631 ENSG00000110900
14  ENSG00000135643 NA KCNMB4 potassium large conductance calcium-activated channel, subfamily M, beta member 4 27345 ENSG00000135643
15  ENSG00000158887 NA MPZ myelin protein zero 4359 ENSG00000158887
16  ENSG00000162951 NA LRRTM1 leucine rich repeat transmembrane neuronal 1 347730 ENSG00000162951
17  ENSG00000154654 NA NCAM2 neural cell adhesion molecule 2 4685 ENSG00000154654
18  ENSG00000184564 NA SLITRK6 SLIT and NTRK-like family, member 6 84189 ENSG00000184564
19  ENSG00000164626 NA KCNK5 potassium channel, subfamily K, member 5 8645 ENSG00000164626
20  ENSG00000113494 NA PRLR prolactin receptor 5618 ENSG00000113494
21  ENSG00000163873 NA GRIK3 glutamate receptor, ionotropic, kainate 3 2899 ENSG00000163873
22  ENSG00000237515 NA SHISA9 shisa homolog 9 (Xenopus laevis) 729993 ENSG00000237515
23  ENSG00000123560 NA PLP1 proteolipid protein 1 5354 ENSG00000123560
24  ENSG00000196338 NA NLGN3 neuroligin 3 54413 ENSG00000196338
25  ENSG00000065361 NA ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 2065 ENSG00000065361
26  ENSG00000111728 NA ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 6489 ENSG00000111728
27  ENSG00000144339 NA TMEFF2 transmembrane protein with EGF-like and two follistatin-like domains 2 23671 ENSG00000144339
28  ENSG00000149571 NA KIRREL3 kin of IRRE like 3 (Drosophila) 84623 ENSG00000149571
29  ENSG00000206579 NA XKR4 XK, Kell blood group complex subunit-related family, member 4 114786 ENSG00000206579
30  ENSG00000198910 NA L1CAM L1 cell adhesion molecule 3897 ENSG00000198910
31  ENSG00000182272 NA B4GALNT4 beta-1,4-N-acetyl-galactosaminyl transferase 4 338707 ENSG00000182272


Database:cellular component       Name:cell surface       ID:GO:0009986
C=495; O=7; E=1.74; R=4.02; rawP=0.0017; adjP=0.0244
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000196338 NA NLGN3 neuroligin 3 54413 ENSG00000196338
2  ENSG00000179915 NA NRXN1 neurexin 1 9378 ENSG00000179915
3  ENSG00000162951 NA LRRTM1 leucine rich repeat transmembrane neuronal 1 347730 ENSG00000162951
4  ENSG00000136378 NA ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7 11173 ENSG00000136378
5  ENSG00000198910 NA L1CAM L1 cell adhesion molecule 3897 ENSG00000198910
6  ENSG00000113494 NA PRLR prolactin receptor 5618 ENSG00000113494
7  ENSG00000146013 NA GFRA3 GDNF family receptor alpha 3 2676 ENSG00000146013


Database:cellular component       Name:integral to membrane       ID:GO:0016021
C=5321; O=30; E=18.72; R=1.60; rawP=0.0018; adjP=0.0244
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000114812 NA VIPR1 vasoactive intestinal peptide receptor 1 7433 ENSG00000114812
2  ENSG00000112077 NA RHAG Rh-associated glycoprotein 6005 ENSG00000112077
3  ENSG00000137070 NA IL11RA interleukin 11 receptor, alpha 3590 ENSG00000137070
4  ENSG00000185985 NA SLITRK2 SLIT and NTRK-like family, member 2 84631 ENSG00000185985
5  ENSG00000046653 NA GPM6B glycoprotein M6B 2824 ENSG00000046653
6  ENSG00000089356 NA FXYD3 FXYD domain containing ion transport regulator 3 5349 ENSG00000089356
7  ENSG00000189409 NA MMP23B matrix metallopeptidase 23B 8510 ENSG00000189409
8  ENSG00000179915 NA NRXN1 neurexin 1 9378 ENSG00000179915
9  ENSG00000117069 NA ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 81849 ENSG00000117069
10  ENSG00000147255 NA IGSF1 immunoglobulin superfamily, member 1 3547 ENSG00000147255
11  ENSG00000021645 NA NRXN3 neurexin 3 9369 ENSG00000021645
12  ENSG00000110900 NA TSPAN11 tetraspanin 11 441631 ENSG00000110900
13  ENSG00000135643 NA KCNMB4 potassium large conductance calcium-activated channel, subfamily M, beta member 4 27345 ENSG00000135643
14  ENSG00000158887 NA MPZ myelin protein zero 4359 ENSG00000158887
15  ENSG00000162951 NA LRRTM1 leucine rich repeat transmembrane neuronal 1 347730 ENSG00000162951
16  ENSG00000154654 NA NCAM2 neural cell adhesion molecule 2 4685 ENSG00000154654
17  ENSG00000184564 NA SLITRK6 SLIT and NTRK-like family, member 6 84189 ENSG00000184564
18  ENSG00000164626 NA KCNK5 potassium channel, subfamily K, member 5 8645 ENSG00000164626
19  ENSG00000113494 NA PRLR prolactin receptor 5618 ENSG00000113494
20  ENSG00000163873 NA GRIK3 glutamate receptor, ionotropic, kainate 3 2899 ENSG00000163873
21  ENSG00000237515 NA SHISA9 shisa homolog 9 (Xenopus laevis) 729993 ENSG00000237515
22  ENSG00000123560 NA PLP1 proteolipid protein 1 5354 ENSG00000123560
23  ENSG00000196338 NA NLGN3 neuroligin 3 54413 ENSG00000196338
24  ENSG00000065361 NA ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 2065 ENSG00000065361
25  ENSG00000111728 NA ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 6489 ENSG00000111728
26  ENSG00000144339 NA TMEFF2 transmembrane protein with EGF-like and two follistatin-like domains 2 23671 ENSG00000144339
27  ENSG00000149571 NA KIRREL3 kin of IRRE like 3 (Drosophila) 84623 ENSG00000149571
28  ENSG00000206579 NA XKR4 XK, Kell blood group complex subunit-related family, member 4 114786 ENSG00000206579
29  ENSG00000198910 NA L1CAM L1 cell adhesion molecule 3897 ENSG00000198910
30  ENSG00000182272 NA B4GALNT4 beta-1,4-N-acetyl-galactosaminyl transferase 4 338707 ENSG00000182272


Database:cellular component       Name:plasma membrane part       ID:GO:0044459
C=1918; O=15; E=6.75; R=2.22; rawP=0.0022; adjP=0.0248
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000021645 NA NRXN3 neurexin 3 9369 ENSG00000021645
2  ENSG00000114812 NA VIPR1 vasoactive intestinal peptide receptor 1 7433 ENSG00000114812
3  ENSG00000112077 NA RHAG Rh-associated glycoprotein 6005 ENSG00000112077
4  ENSG00000135643 NA KCNMB4 potassium large conductance calcium-activated channel, subfamily M, beta member 4 27345 ENSG00000135643
5  ENSG00000137070 NA IL11RA interleukin 11 receptor, alpha 3590 ENSG00000137070
6  ENSG00000158887 NA MPZ myelin protein zero 4359 ENSG00000158887
7  ENSG00000164626 NA KCNK5 potassium channel, subfamily K, member 5 8645 ENSG00000164626
8  ENSG00000089356 NA FXYD3 FXYD domain containing ion transport regulator 3 5349 ENSG00000089356
9  ENSG00000163873 NA GRIK3 glutamate receptor, ionotropic, kainate 3 2899 ENSG00000163873
10  ENSG00000146013 NA GFRA3 GDNF family receptor alpha 3 2676 ENSG00000146013
11  ENSG00000237515 NA SHISA9 shisa homolog 9 (Xenopus laevis) 729993 ENSG00000237515
12  ENSG00000196338 NA NLGN3 neuroligin 3 54413 ENSG00000196338
13  ENSG00000065361 NA ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 2065 ENSG00000065361
14  ENSG00000179915 NA NRXN1 neurexin 1 9378 ENSG00000179915
15  ENSG00000198910 NA L1CAM L1 cell adhesion molecule 3897 ENSG00000198910


Database:cellular component       Name:membrane part       ID:GO:0044425
C=6154; O=32; E=21.65; R=1.48; rawP=0.0046; adjP=0.0376
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000114812 NA VIPR1 vasoactive intestinal peptide receptor 1 7433 ENSG00000114812
2  ENSG00000112077 NA RHAG Rh-associated glycoprotein 6005 ENSG00000112077
3  ENSG00000137070 NA IL11RA interleukin 11 receptor, alpha 3590 ENSG00000137070
4  ENSG00000185985 NA SLITRK2 SLIT and NTRK-like family, member 2 84631 ENSG00000185985
5  ENSG00000046653 NA GPM6B glycoprotein M6B 2824 ENSG00000046653
6  ENSG00000089356 NA FXYD3 FXYD domain containing ion transport regulator 3 5349 ENSG00000089356
7  ENSG00000189409 NA MMP23B matrix metallopeptidase 23B 8510 ENSG00000189409
8  ENSG00000146013 NA GFRA3 GDNF family receptor alpha 3 2676 ENSG00000146013
9  ENSG00000100146 NA SOX10 SRY (sex determining region Y)-box 10 6663 ENSG00000100146
10  ENSG00000179915 NA NRXN1 neurexin 1 9378 ENSG00000179915
11  ENSG00000117069 NA ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 81849 ENSG00000117069
12  ENSG00000147255 NA IGSF1 immunoglobulin superfamily, member 1 3547 ENSG00000147255
13  ENSG00000021645 NA NRXN3 neurexin 3 9369 ENSG00000021645
14  ENSG00000110900 NA TSPAN11 tetraspanin 11 441631 ENSG00000110900
15  ENSG00000135643 NA KCNMB4 potassium large conductance calcium-activated channel, subfamily M, beta member 4 27345 ENSG00000135643
16  ENSG00000158887 NA MPZ myelin protein zero 4359 ENSG00000158887
17  ENSG00000162951 NA LRRTM1 leucine rich repeat transmembrane neuronal 1 347730 ENSG00000162951
18  ENSG00000154654 NA NCAM2 neural cell adhesion molecule 2 4685 ENSG00000154654
19  ENSG00000184564 NA SLITRK6 SLIT and NTRK-like family, member 6 84189 ENSG00000184564
20  ENSG00000164626 NA KCNK5 potassium channel, subfamily K, member 5 8645 ENSG00000164626
21  ENSG00000113494 NA PRLR prolactin receptor 5618 ENSG00000113494
22  ENSG00000163873 NA GRIK3 glutamate receptor, ionotropic, kainate 3 2899 ENSG00000163873
23  ENSG00000237515 NA SHISA9 shisa homolog 9 (Xenopus laevis) 729993 ENSG00000237515
24  ENSG00000123560 NA PLP1 proteolipid protein 1 5354 ENSG00000123560
25  ENSG00000196338 NA NLGN3 neuroligin 3 54413 ENSG00000196338
26  ENSG00000065361 NA ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 2065 ENSG00000065361
27  ENSG00000111728 NA ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 6489 ENSG00000111728
28  ENSG00000144339 NA TMEFF2 transmembrane protein with EGF-like and two follistatin-like domains 2 23671 ENSG00000144339
29  ENSG00000149571 NA KIRREL3 kin of IRRE like 3 (Drosophila) 84623 ENSG00000149571
30  ENSG00000206579 NA XKR4 XK, Kell blood group complex subunit-related family, member 4 114786 ENSG00000206579
31  ENSG00000198910 NA L1CAM L1 cell adhesion molecule 3897 ENSG00000198910
32  ENSG00000182272 NA B4GALNT4 beta-1,4-N-acetyl-galactosaminyl transferase 4 338707 ENSG00000182272


Database:cellular component       Name:growth cone       ID:GO:0030426
C=93; O=3; E=0.33; R=9.17; rawP=0.0043; adjP=0.0376
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000128872 NA TMOD2 tropomodulin 2 (neuronal) 29767 ENSG00000128872
2  ENSG00000179915 NA NRXN1 neurexin 1 9378 ENSG00000179915
3  ENSG00000162951 NA LRRTM1 leucine rich repeat transmembrane neuronal 1 347730 ENSG00000162951




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).